Search results for "Serum IL-6"

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Evaluation of pretreatment serum interleukin-6 and tumour necrosis factor alpha as a potential biomarker for recurrence in patients with oral squamou…

2014

Background Oral squamous cell carcinoma (OSCC) constitutes 3 percent of all cancers with predominant occurrence in middle aged and elderly males. Tumour recurrence worsens disease prognosis and decreases quality of life in patients with OSCC. Proinflammatory cytokines such as interleukin-6 (IL-6) and tumour necrosis factor alpha (TNF-α) have been suggested to play a certain role in variety of tumours. The aim of this study was to investigate the relationship of pretreatment serum IL-6 and TNF-α levels on tumour recurrence in patients with OSCC in order to identify potential biomarkers for the early detection of disease recurrence. Material and Methods The patients with newly diagnosed OSCC …

OncologyAdultMalemedicine.medical_specialtyPathologyOdontología03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicinemedicineCarcinomaSerum IL-6 ; serum TNF-α ; oral cancer ; recurrenceBiomarkers TumorHumansProspective StudiesRisk factorProspective cohort studyGeneral DentistrySurvival analysisEarly Detection of CancerAgedMouth neoplasmOral Medicine and Pathologybusiness.industryInterleukin-6Tumor Necrosis Factor-alphaResearchCancer030206 dentistryMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la salud3. Good healthLog-rank teststomatognathic diseasesOtorhinolaryngology030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASCarcinoma Squamous CellBiomarker (medicine)SurgeryFemaleMouth NeoplasmsNeoplasm Recurrence LocalbusinessMedicina oral, patologia oral y cirugia bucal
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